PhytoCellTec™ Malus Domestica
Plant stem cells for skin stem cell protection
PhytoCellTec™ Malus Domestica is a patented liposomal preparation of apple stem cells derived from the ‘Uttwiler Spätlauber’, a rare Swiss apple variety. These apple stem cells are rich in epigenetic factors and metabolites, which ensures the longevity of skin cells. PhytoCellTec™ Malus Domestica has been shown to protect skin stem cells while also delaying the senescence of hair follicles. PhytoCellTec™ Malus Domestica succeeds in delivering a revolutionary anti-aging performance for real rejuvenation.
Mibelle Biochemistry has developed a novel plant cell culture technology (PhytoCellTec™) that enables the large-scale cultivation of callus (stem) cells from rare and protected plant species, such as Malus Domestica. The PhytoCellTec™ technology, which was recognized at the UN Conference Rio+20 as an Eco breakthrough, delivers a highly sustainable sourcing of this active. You can find further information on our PhytoCellTec™ website.
PhytoCellTec™ Malus Domestica was the first ingredient based on plant stem cells on the cosmetic market. The topical use of PhytoCellTec™ Malus Domestica is patented in the USA (US 9,155,916 B2 / US 8,580,320 B2) and in Korea (10-1470632).


Uttwiler Spätlauber is a variety of a Swiss apple (Malus domestica) that is derived from a seedling planted in the middle of the 18th century. It was very famous for its excellent storability without shriveling. Uttwiler Spätlauber apples have especially long-living tissue stem cells, while their specific composition of metabolites leads to incredible storability and longevity properties.




Plant Stem Cell Extract for Longevity of Skin and Hair SOEFW 05 08
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Potential of Plant Cells in Culture for Cosmetic Application Phytochem Rev 2008
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Stimulation of stem cells for real skin rejuvenation CosmeticsDesign 08 2008
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Stimuli for Skin Stem Cells for Real Skin Rejuvenation HPC Anti-Aging Beauty Inside April 09
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An Apple A Day SPC 02 2010
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Stimulating Epidermal Regeneration with Plant-Derived Stem Cells C&T May 2010
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